According to website Holymoly.com, U2 will play the Pyramid Stage on the Friday night, with Beyonce taking the top slot on the Saturday, while Coldplay have been given the prestigious closing slot on the Sunday night.
He said: "There's an American artist that I've been wanting to have for years and yonks and yonks and yonks."
Because U2 were forced to cancel last year's appearance, Michael has always said the band would perform in 2011, while Coldplay have been rumoured for months.
Last year, Gorillaz replaced U2 as headliners, with Muse and Stevie Wonder talking the other places on the bill.